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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00008
Genomic locus: chr3:12327760-12522419
Size/Length: 194659 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_015869
Gene Symbol: PPARG
Chromosome: chr3
TSS: 12329348 (Transcription start site)
TES: 12475855 (Transcription end site)
Strand: +
Number of Exons: 7
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr3:12327760-12522419
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00008

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C003957 SE_00008 chr3 12327760 12366515 38755 3100
C003958 SE_00008 chr3 12367051 12371244 4193 1060.05
C003959 SE_00008 chr3 12371274 12403887 32613 3100
C003960 SE_00008 chr3 12403975 12406550 2575 1128.23
C003961 SE_00008 chr3 12407396 12409333 1937 225.33
C003962 SE_00008 chr3 12409423 12423379 13956 3100
C003963 SE_00008 chr3 12423444 12428125 4681 627.42
C003964 SE_00008 chr3 12429155 12441182 12027 3100
C003965 SE_00008 chr3 12441204 12455629 14425 3167.4
C003966 SE_00008 chr3 12455646 12460981 5335 1452.42
C003967 SE_00008 chr3 12460982 12474620 13638 1540.31
C003968 SE_00008 chr3 12474722 12483905 9183 3100
C003969 SE_00008 chr3 12483946 12486309 2363 153.04
C003970 SE_00008 chr3 12491038 12492440 1402 147.62
C003971 SE_00008 chr3 12492671 12498521 5850 2399.68
C003972 SE_00008 chr3 12499168 12506230 7062 2142.95
C003973 SE_00008 chr3 12516742 12520152 3410 1354.51
C003974 SE_00008 chr3 12520648 12522419 1771 216.16