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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00015
Genomic locus: chr10:114708122-114899787
Size/Length: 191665 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_001146274
Gene Symbol: TCF7L2
Chromosome: chr10
TSS: 114710008 (Transcription start site)
TES: 114927436 (Transcription end site)
Strand: +
Number of Exons: 15
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr10:114708122-114899787
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00015

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C001067 SE_00015 chr10 114708122 114719482 11360 3100
C001068 SE_00015 chr10 114720846 114722655 1809 151.78
C001069 SE_00015 chr10 114722766 114727381 4615 444.83
C001070 SE_00015 chr10 114731791 114733379 1588 290.47
C001071 SE_00015 chr10 114745009 114747306 2297 203.97
C001072 SE_00015 chr10 114753297 114758735 5438 1160.77
C001073 SE_00015 chr10 114760010 114762473 2463 269.22
C001074 SE_00015 chr10 114765020 114766799 1779 343.03
C001075 SE_00015 chr10 114770899 114773015 2116 296.78
C001076 SE_00015 chr10 114775986 114777408 1422 175.14
C001077 SE_00015 chr10 114778483 114779405 922 100.65
C001078 SE_00015 chr10 114779593 114783018 3425 1427.77
C001079 SE_00015 chr10 114785818 114789538 3720 900.68
C001080 SE_00015 chr10 114793563 114829014 35451 3100
C001081 SE_00015 chr10 114830062 114835349 5287 2104.09
C001082 SE_00015 chr10 114836095 114837628 1533 159.47
C001083 SE_00015 chr10 114838544 114841604 3060 341.14
C001084 SE_00015 chr10 114842925 114850682 7757 2665.92
C001085 SE_00015 chr10 114851489 114857456 5967 1803.24
C001086 SE_00015 chr10 114858372 114860570 2198 328.82
C001087 SE_00015 chr10 114861809 114869152 7343 3100
C001088 SE_00015 chr10 114869702 114875808 6106 1473.17
C001089 SE_00015 chr10 114886558 114895279 8721 3100
C001090 SE_00015 chr10 114898293 114899787 1494 160.18