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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00035
Genomic locus: chr15:67335503-67451448
Size/Length: 115945 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_001145102
Gene Symbol: SMAD3
Chromosome: chr15
TSS: 67418053 (Transcription start site)
TES: 67487533 (Transcription end site)
Strand: +
Number of Exons: 9
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr15:67335503-67451448
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00035

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C002324 SE_00035 chr15 67335503 67337504 2001 797.02
C002325 SE_00035 chr15 67337579 67338785 1206 123.95
C002326 SE_00035 chr15 67339797 67344606 4809 3100
C002327 SE_00035 chr15 67350476 67352825 2349 729.77
C002328 SE_00035 chr15 67355373 67363202 7829 3100
C002329 SE_00035 chr15 67366306 67369231 2925 448.75
C002330 SE_00035 chr15 67371895 67376467 4572 2109.66
C002331 SE_00035 chr15 67382644 67384759 2115 241.82
C002332 SE_00035 chr15 67389471 67392242 2771 517.55
C002333 SE_00035 chr15 67395231 67404229 8998 3100
C002334 SE_00035 chr15 67405586 67421467 15881 3100
C002335 SE_00035 chr15 67422545 67424832 2287 341.97
C002336 SE_00035 chr15 67425259 67432414 7155 3100
C002337 SE_00035 chr15 67433164 67436466 3302 767.6
C002338 SE_00035 chr15 67436757 67445463 8706 3100
C002339 SE_00035 chr15 67449455 67451448 1993 335.67