Super Enhancer Details

General details

Super-Enhancer ID:	SE_00116
Genomic locus:	chr22:36715281-36785261
Size/Length:	69980 bp
Genome:	Human - hg19
Cell/Tissue:	Adipose Nuclei
Factor(s) Used:	H3K27ac - (Used to define enhancers) H3K27ac - (Used to rank SEs)
Input/WCE:	GSM621401
Reference:	Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID:	NM_145343
Gene Symbol:	APOL1
Chromosome:	chr22
TSS:	36649116 (Transcription start site)
TES:	36663577 (Transcription end site)
Strand:	+
Number of Exons:	5
External Links:

Software and parameters used

Stitching Distance:	12.5 kb
Read Mapping:	Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling:	MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
TSS Exclusive Zone:	+/- 2 kb
Enhancer-gene Assignment:	Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence

>chr22:36715281-36785261
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00116

Constituent ID	SE ID	Chrom	Start	End	Constituent Size	MACS score
C003918	SE_00116	chr22	36715281	36734762	19481	3100
C003919	SE_00116	chr22	36734875	36736412	1537	308.33
C003920	SE_00116	chr22	36736450	36738088	1638	327.9
C003921	SE_00116	chr22	36739327	36740734	1407	176.97
C003922	SE_00116	chr22	36741927	36743611	1684	217.82
C003923	SE_00116	chr22	36744550	36773501	28951	2323.23
C003924	SE_00116	chr22	36773956	36778456	4500	901.83
C003925	SE_00116	chr22	36780434	36785261	4827	3100