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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00118
Genomic locus: chr10:6182494-6261722
Size/Length: 79228 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_004566
Gene Symbol: PFKFB3
Chromosome: chr10
TSS: 6244839 (Transcription start site)
TES: 6277507 (Transcription end site)
Strand: +
Number of Exons: 15
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr10:6182494-6261722
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00118

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C000713 SE_00118 chr10 6182494 6184852 2358 910.89
C000714 SE_00118 chr10 6185420 6189101 3681 798.25
C000715 SE_00118 chr10 6192579 6196143 3564 746.38
C000716 SE_00118 chr10 6198788 6201398 2610 504.22
C000717 SE_00118 chr10 6203859 6208173 4314 3100
C000718 SE_00118 chr10 6208787 6222014 13227 3100
C000719 SE_00118 chr10 6222846 6225924 3078 753.11
C000720 SE_00118 chr10 6226341 6227855 1514 177.6
C000721 SE_00118 chr10 6228266 6231334 3068 700.11
C000722 SE_00118 chr10 6231971 6247895 15924 3100
C000723 SE_00118 chr10 6249566 6251648 2082 264.09
C000724 SE_00118 chr10 6252685 6257496 4811 1199.24
C000725 SE_00118 chr10 6260396 6261722 1326 109.3