Super Enhancer Details

General details

Super-Enhancer ID:	SE_00143
Genomic locus:	chr2:227589031-227667917
Size/Length:	78886 bp
Genome:	Human - hg19
Cell/Tissue:	Adipose Nuclei
Factor(s) Used:	H3K27ac - (Used to define enhancers) H3K27ac - (Used to rank SEs)
Input/WCE:	GSM621401
Reference:	Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID:	NM_005544
Gene Symbol:	IRS1
Chromosome:	chr2
TSS:	227596032 (Transcription start site)
TES:	227663506 (Transcription end site)
Strand:	-
Number of Exons:	2
External Links:

Software and parameters used

Stitching Distance:	12.5 kb
Read Mapping:	Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling:	MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
TSS Exclusive Zone:	+/- 2 kb
Enhancer-gene Assignment:	Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence

>chr2:227589031-227667917
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00143

Constituent ID	SE ID	Chrom	Start	End	Constituent Size	MACS score
C003604	SE_00143	chr2	227589031	227590987	1956	212.12
C003605	SE_00143	chr2	227597349	227600685	3336	477.12
C003606	SE_00143	chr2	227602060	227611610	9550	1355.83
C003607	SE_00143	chr2	227614768	227640308	25540	1410.1
C003608	SE_00143	chr2	227642958	227644327	1369	117.36
C003609	SE_00143	chr2	227646386	227648218	1832	225.33
C003610	SE_00143	chr2	227650776	227667917	17141	3100