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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00145
Genomic locus: chr2:46523122-46595093
Size/Length: 71971 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_001430
Gene Symbol: EPAS1
Chromosome: chr2
TSS: 46524540 (Transcription start site)
TES: 46613842 (Transcription end site)
Strand: +
Number of Exons: 16
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr2:46523122-46595093
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00145

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C003209 SE_00145 chr2 46523122 46551339 28217 3100
C003210 SE_00145 chr2 46551383 46568193 16810 3100
C003211 SE_00145 chr2 46569787 46570977 1190 97.6
C003212 SE_00145 chr2 46573059 46580955 7896 1273.95
C003213 SE_00145 chr2 46590342 46591943 1601 136.62
C003214 SE_00145 chr2 46592997 46595093 2096 332.31