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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00169
Genomic locus: chr18:46229136-46336294
Size/Length: 107158 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_001190823
Gene Symbol: SMAD7
Chromosome: chr18
TSS: 46446222 (Transcription start site)
TES: 46477081 (Transcription end site)
Strand: -
Number of Exons: 4
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr18:46229136-46336294
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00169

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C002837 SE_00169 chr18 46229136 46230071 935 92.9
C002838 SE_00169 chr18 46235286 46236735 1449 139.34
C002839 SE_00169 chr18 46238264 46240941 2677 722.08
C002840 SE_00169 chr18 46241656 46242807 1151 120.67
C002841 SE_00169 chr18 46252254 46255350 3096 266.72
C002842 SE_00169 chr18 46264945 46267508 2563 336.44
C002843 SE_00169 chr18 46267634 46273096 5462 3100
C002844 SE_00169 chr18 46274285 46280243 5958 3219.84
C002845 SE_00169 chr18 46280318 46282774 2456 307.71
C002846 SE_00169 chr18 46288171 46290528 2357 483.51
C002847 SE_00169 chr18 46292844 46294858 2014 212.33
C002848 SE_00169 chr18 46295528 46296779 1251 129.03
C002849 SE_00169 chr18 46302588 46310594 8006 3100
C002850 SE_00169 chr18 46313269 46319783 6514 3100
C002851 SE_00169 chr18 46326627 46329711 3084 452.21
C002852 SE_00169 chr18 46331619 46336294 4675 732.09