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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00297
Genomic locus: chr18:46448577-46484802
Size/Length: 36225 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_001190823
Gene Symbol: SMAD7
Chromosome: chr18
TSS: 46446222 (Transcription start site)
TES: 46477081 (Transcription end site)
Strand: -
Number of Exons: 4
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr18:46448577-46484802
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00297

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C002853 SE_00297 chr18 46448577 46450583 2006 373.79
C002854 SE_00297 chr18 46450614 46453330 2716 1579.12
C002855 SE_00297 chr18 46453448 46463365 9917 3100
C002856 SE_00297 chr18 46463595 46484802 21207 3100