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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00377
Genomic locus: chr14:61937453-62055873
Size/Length: 118420 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_001530
Gene Symbol: HIF1A
Chromosome: chr14
TSS: 62162118 (Transcription start site)
TES: 62214977 (Transcription end site)
Strand: +
Number of Exons: 14
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr14:61937453-62055873
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00377

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C002019 SE_00377 chr14 61937453 61940415 2962 282.53
C002020 SE_00377 chr14 61941128 61948236 7108 3100
C002021 SE_00377 chr14 61955121 61961155 6034 817.57
C002022 SE_00377 chr14 61964671 61966595 1924 175.62
C002023 SE_00377 chr14 61969527 61970925 1398 103.55
C002024 SE_00377 chr14 61982125 61985224 3099 324.71
C002025 SE_00377 chr14 61990315 61994494 4179 553.24
C002026 SE_00377 chr14 61997663 61998918 1255 126.13
C002027 SE_00377 chr14 62003306 62005848 2542 262.78
C002028 SE_00377 chr14 62008989 62011610 2621 645.49
C002029 SE_00377 chr14 62018629 62021661 3032 474.8
C002030 SE_00377 chr14 62026807 62029961 3154 960.98
C002031 SE_00377 chr14 62030264 62034758 4494 346.7
C002032 SE_00377 chr14 62036220 62038137 1917 407.56
C002033 SE_00377 chr14 62048182 62050301 2119 384.12
C002034 SE_00377 chr14 62051763 62055873 4110 2300.41