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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00425
Genomic locus: chr8:134227875-134311366
Size/Length: 83491 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_006096
Gene Symbol: NDRG1
Chromosome: chr8
TSS: 134249413 (Transcription start site)
TES: 134309547 (Transcription end site)
Strand: -
Number of Exons: 14
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr8:134227875-134311366
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00425

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C005821 SE_00425 chr8 134227875 134230274 2399 421.13
C005822 SE_00425 chr8 134239458 134240853 1395 104.04
C005823 SE_00425 chr8 134242193 134245712 3519 1281.54
C005824 SE_00425 chr8 134248620 134251650 3030 1837.67
C005825 SE_00425 chr8 134259349 134260740 1391 97.83
C005826 SE_00425 chr8 134261292 134262357 1065 92.26
C005827 SE_00425 chr8 134270370 134273420 3050 314.63
C005828 SE_00425 chr8 134276469 134277977 1508 286.7
C005829 SE_00425 chr8 134285087 134286646 1559 172.42
C005830 SE_00425 chr8 134291557 134292736 1179 111.46
C005831 SE_00425 chr8 134297596 134299618 2022 220.58
C005832 SE_00425 chr8 134301340 134311366 10026 3100