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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00437
Genomic locus: chr1:154377018-154436889
Size/Length: 59871 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_181359
Gene Symbol: IL6R
Chromosome: chr1
TSS: 154377668 (Transcription start site)
TES: 154441926 (Transcription end site)
Strand: +
Number of Exons: 10
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr1:154377018-154436889
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00437

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C000468 SE_00437 chr1 154377018 154382465 5447 3100
C000469 SE_00437 chr1 154390273 154397370 7097 3100
C000470 SE_00437 chr1 154399481 154401751 2270 649.94
C000471 SE_00437 chr1 154403931 154408447 4516 2727.59
C000472 SE_00437 chr1 154410501 154413087 2586 310.88
C000473 SE_00437 chr1 154413491 154415294 1803 162.27
C000474 SE_00437 chr1 154417920 154419740 1820 284.73
C000475 SE_00437 chr1 154425294 154427061 1767 345.78
C000476 SE_00437 chr1 154435280 154436889 1609 332.78