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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00485
Genomic locus: chr21:35012779-35077164
Size/Length: 64385 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_003024
Gene Symbol: ITSN1
Chromosome: chr21
TSS: 35014783 (Transcription start site)
TES: 35261609 (Transcription end site)
Strand: +
Number of Exons: 40
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr21:35012779-35077164
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00485

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C003774 SE_00485 chr21 35012779 35019787 7008 3100
C003775 SE_00485 chr21 35019898 35021826 1928 178.64
C003776 SE_00485 chr21 35023026 35024982 1956 136.37
C003777 SE_00485 chr21 35026305 35035831 9526 915.96
C003778 SE_00485 chr21 35038742 35041748 3006 358.45
C003779 SE_00485 chr21 35042077 35043947 1870 227.75
C003780 SE_00485 chr21 35049860 35051584 1724 328.9
C003781 SE_00485 chr21 35054545 35059599 5054 2193.4
C003782 SE_00485 chr21 35059600 35062256 2656 359.22
C003783 SE_00485 chr21 35063066 35064161 1095 116.56
C003784 SE_00485 chr21 35067230 35069531 2301 303.89
C003785 SE_00485 chr21 35069578 35071743 2165 421.94
C003786 SE_00485 chr21 35075406 35077164 1758 264.23