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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00490
Genomic locus: chr10:120964974-121078144
Size/Length: 113170 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_005308
Gene Symbol: GRK5
Chromosome: chr10
TSS: 120967196 (Transcription start site)
TES: 121215131 (Transcription end site)
Strand: +
Number of Exons: 16
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr10:120964974-121078144
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00490

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C001109 SE_00490 chr10 120964974 120970316 5342 2521.49
C001110 SE_00490 chr10 120970401 120972386 1985 232.95
C001111 SE_00490 chr10 120980686 120982827 2141 386.31
C001112 SE_00490 chr10 120992065 120994428 2363 376.02
C001113 SE_00490 chr10 120996635 120998433 1798 145.52
C001114 SE_00490 chr10 121005687 121007329 1642 216.23
C001115 SE_00490 chr10 121009751 121015716 5965 2110.25
C001116 SE_00490 chr10 121023495 121025013 1518 201.64
C001117 SE_00490 chr10 121027389 121033274 5885 1872.41
C001118 SE_00490 chr10 121033821 121035265 1444 127.91
C001119 SE_00490 chr10 121039286 121041435 2149 269.44
C001120 SE_00490 chr10 121047726 121050833 3107 375.83
C001121 SE_00490 chr10 121060377 121062038 1661 213.84
C001122 SE_00490 chr10 121064226 121066665 2439 336.26
C001123 SE_00490 chr10 121073659 121078144 4485 722.88