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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00591
Genomic locus: chr15:48893707-48965905
Size/Length: 72198 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_000138
Gene Symbol: FBN1
Chromosome: chr15
TSS: 48700502 (Transcription start site)
TES: 48937985 (Transcription end site)
Strand: -
Number of Exons: 66
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr15:48893707-48965905
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00591

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C002180 SE_00591 chr15 48893707 48897458 3751 403.7
C002181 SE_00591 chr15 48899959 48901374 1415 107.21
C002182 SE_00591 chr15 48904746 48910729 5983 756.98
C002183 SE_00591 chr15 48919022 48920916 1894 248.31
C002184 SE_00591 chr15 48921722 48926611 4889 700.59
C002185 SE_00591 chr15 48927718 48930528 2810 230.53
C002186 SE_00591 chr15 48932791 48941042 8251 3100
C002187 SE_00591 chr15 48944626 48948221 3595 375.55
C002188 SE_00591 chr15 48959495 48961010 1515 324.75
C002189 SE_00591 chr15 48962380 48965905 3525 613.05