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Super Enhancer Details

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General details

Super-Enhancer ID: SE_00593
Genomic locus: chr16:48387083-48429049
Size/Length: 41966 bp
Genome: Human - hg19
Cell/Tissue: Adipose Nuclei
Factor(s) Used: H3K27ac - (Used to define enhancers)
H3K27ac - (Used to rank SEs)
Input/WCE: GSM621401
Reference: Hnisz D. et al., 2013 Cell - 24119843

Associated gene details

RefSeq ID: NM_001006610
Gene Symbol: SIAH1
Chromosome: chr16
TSS: 48394453 (Transcription start site)
TES: 48419229 (Transcription end site)
Strand: -
Number of Exons: 2
External Links:

Software and parameters used

Read Mapping: Bowtie (version 0.12.9) with parameters -k 2, -m 2, -n 2, -best.
Peak Calling: MACS (version 1.4.1) with parameters -p 1e-9,-keep-dup = auto, -w -S -space = 50
Stitching Distance: 12.5 kb
TSS Exclusive Zone: +/- 2 kb
Enhancer-gene Assignment: Genes were assigned to SEs within a 50 kb window. In cases where experimentally verified enhancer-gene assignments were available, genes were assigned to enhancers based on those studies.

FASTA sequence



>chr16:48387083-48429049
Sequence preview unavailable; use Download FASTA.

Wiggle files

Download Wiggle (WIG) files, generated by original data source.

Constituents of Super-enhancer - SE_00593

Constituent ID SE ID Chrom Start End Constituent Size MACS score
C002495 SE_00593 chr16 48387083 48387973 890 93.22
C002496 SE_00593 chr16 48388061 48392446 4385 628.14
C002497 SE_00593 chr16 48395283 48397041 1758 215.52
C002498 SE_00593 chr16 48397942 48402042 4100 3100
C002499 SE_00593 chr16 48405064 48408450 3386 369.23
C002500 SE_00593 chr16 48410441 48411773 1332 127.02
C002501 SE_00593 chr16 48412161 48414376 2215 215.32
C002502 SE_00593 chr16 48414958 48420418 5460 3100
C002503 SE_00593 chr16 48426641 48429049 2408 1195.51